About page

The PEREGRINE (Predicted by Experimental Results: Enhancer-Gene Relationships Illustrated by a Nexus of Evidence) enhancer-gene links incorporate publicly available experimental data from ChIA-PET, eQTL, and Hi-C assays across 78 cell and tissue types to link 449,627 enhancers to 17,643 protein-coding genes. These enhancer-gene links are made available through the new Enhancer module of the PANTHER database and website where the user may easily access the evidence for each enhancer-gene link, as well as query by target gene and enhancer location.

This work is supported by NIH/NIEHS: P01CA196569-01A1.

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Team

Caitlin Mills (lead developer)

Anushya Muruganujan (software engineer)

Dustin Ebert (bioinformatics programmer)

Paul D. Thomas (investigator)

Huaiyu Mi (principal investigator)

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Publications

PEREGRINE: A genome-wide prediction of enhancer to gene relationships supported by experimental evidence
Caitlin Mills, Anushya Muruganujan, Dustin Ebert, Crystal N Marconett, Juan Pablo Lewinger, Paul D Thomas, Huaiyu Mi
PLoS One. 2020 Dec 15;15(12):e0243791. doi: 10.1371/journal.pone.0243791. eCollection 2020.

For comments and feedback about the PEREGRINE database, please send email to peregrinefeedback@gmail.com

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